Even when most indicators suggest a low-risk form of neuroblastoma, loss of genetic material on chromosomes 1 and 11 predicts a poor outcome, researchers here reported.
The finding may allow clinicians to improve treatment for the disease, which afflicts about 650 children every year in the U.S., said John Maris, M.D., of Children's Hospital of Philadelphia. "If we can correctly detect risk factors at diagnosis, we can tailor their treatment accordingly," he said.
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